After my last two posts sharing my inquiry with DeepSeek around whether migraine may be a blood platelet disorder (read part 1 here, part 2 here), I received the following email in my inbox from a follower. Since she has given me permission to publish this exchange, I thought I would do so. What this reveals is that while the causes of migraine may be diverse, asking the right questions can lead us to some unconventional and useful answers when it comes to understanding what migraine is. If our bone produces our blood platelets, then its clear that this inquiry needs to be taken further down the rabbit hole as we ask the question: how could building bone and improving bone health potentially reduce migraine incidence by way of its effects on blood platelets? As y last inquiry revealed, there are many reasons why blood platelets can aggregate and dump serotonin, but supporting bone health may be one big part of the missing puzzle in the migraine maize. I’ll chat with DeepSeek about that next, but in the meantime here’s the exchange below:
Marya –
I appreciate this connection. After years of steadily increasing platelet levels, I was finally diagnosed last year with a rare blood/bone marrow disease that causes my body to overproduce platelets. I’ve been seeing an amazing hematologist and I’ve not had a single migraine for 6 or 7 months, likely due to the daily aspirin and iron he has me taking. I’ve had migraines for 20 years. They are 100% gone, with a 95% reduction in general inflammation. I’ve not changed anything else other than aspirin and iron. I read your email and then researched scientific papers online, which appears to support a lot of what is in your AI summary.
I’m just sharing this for your information. If you continue to write on this topic you are welcome to mention my story (without sharing my name to respect my personal information).
I appreciate you just putting information out there so I could make this connection and find the supporting information online.
~ KT
Hi KT –
Thank you for this email. It’s very valuable to have your account. I have read of other cases where people were able to resolve longstanding migraine problems with iron alone. Unfortunately this doesn’t work for everyone. And not everyone’s migraine root cause is the same, but I think this inquiry into migraine as a blood disorder for some is super interesting. I recently heard an interview with a doctor and he said, “Root causes can be diverse, but all of the root causes share one root mechanism: inflammation.” In the same way, there could be many different root causes of blood platelet aggregation, but they might have similar outcomes or affects on the vasculature.
I’d love to learn about more reasons why people might have blood platelet disorders. And yes, looking into the role of bone seems like a next line of inquiry. A quick glance shows that low bone density (which is consistent with fluoride toxicity and low iodine and boron levels, along with other mineral imbalances) and low bone turnover is associated with increased platelet activity and also aggregation.
Women need 20 times more calcium than men. Boron is essential for calcium homeostasis and magnesium retention for strong and healthy bones.
I definitely want to look more into this. So thanks for the lead! I’ll publish your response to me and share it with others in some format soon.
I’m so glad you’ve experienced relief.
Warmly
Marya
Hi Marya!
Thanks for the response. Since you are obviously a curious person, here’s a link https://www.cancerresearchuk.org/about-cancer/myelofibrosis/what-is-myelofibrosis
I had no idea myeloproliferative neoplasm disorders existed (there are multiple types) until I was diagnosed with one of them. I doubt this information is relevant to most people as this is a rare disease, but it’s still an example of someone with platelet issues and a history of migraines seeing major relief from aspirin and iron.
If you need to provide your readers with context, feel free to say mid-40s female, since I want my response anonymous. But maybe it will help someone else also showing years of lab work with increasing platelets!
Have a good weekend!
~ KT
Click here to read my inquiry with DeepSeek on the relationship between bone health and blood platelet levels.
